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Strategic partnership with Essen Instruments Inc.

Essen Instruments Inc.,developer of the IncuCyte™ live-cell imaging system and TCS Cellworks Ltd., developer of the live-cell AngioKit™ an in vitro co-culture model of angiogenesis, have entered into a strategic partnership to promote and distribute live-cell angiogenesis kits compatible with Essen's imaging technology. Angiogenesis is the multi-step process whereby new blood vessels develop. This process plays a key role in many pathological conditions such as cancer.

The IncuCyte^FLR is the latest imaging system from Essen and is designed to enable time-lapse imaging of live-cell fluorescent reporters. The IncuCyte^FLR fits inside a cell culture incubator allowing researchers to gather fluorescent and phase contrast time-lapse images around-the-clock. The system is ideal for monitoring processes which require hours to days such as angiogenesis.

Under the terms of the agreement, TCS will distribute IncuCyte™-compatible AngioKit's™ in Europe, and Essen Instruments will distribute the same kits in North America.

In addition, TCS and Essen will co-market a "GFP Angiokit" for use in association with the IncuCyte^FLR imaging system. The GFP label allows tubule formation to be imaged and quantified in real time, even in the presence of other cell types. This approach enables researchers to follow chemical intervention at many time points, as opposed to a single time point, during the entire multi-day, multi-step angiogenesis process. The kinetic read-out can provide unique insights into drug mechanism.

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